View source for 6jnk


==Crystal structure of Azospirillum brasilense L-arabinose 1-dehydrogenase (NADP-bound form)==
<StructureSection load='6jnk' size='340' side='right'caption='[[6jnk]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jnk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Azospirillum_brasilense Azospirillum brasilense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JNK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jnk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jnk OCA], [https://pdbe.org/6jnk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jnk RCSB], [https://www.ebi.ac.uk/pdbsum/6jnk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jnk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARAA_AZOBR ARAA_AZOBR] Catalyzes the NAD(P)(+)-dependent conversion of L-arabinose to L-arabino-gamma-lactone. Is involved in a degradation pathway of L-arabinose that allows A.brasilense to grow on L-arabinose as a sole carbon source. Prefers NADP(+) to NAD(+) as electron acceptor. Displays high catalytic efficiency for both L-arabinose and D-galactose in vitro. However, the enzyme appears to be involved in the metabolism of L-arabinose but not D-galactose in vivo. To a lesser extent, is also active on D-talose and D-xylose as substrates in vitro, but not with D-arabinose, D-glucose, D-ribose, L-xylose, L-mannose, L-lyxose, and D-fructose.<ref>PMID:16326697</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Azospirillum brasilense]]
[[Category: Large Structures]]
[[Category: Iga C]]
[[Category: Watanabe S]]
[[Category: Watanabe Y]]