View source for 6jsc


==Crystal structure of the H434A variant of the C-terminal domain of HtaA from Corynebacterium glutamicum==
<StructureSection load='6jsc' size='340' side='right'caption='[[6jsc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jsc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JSC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jsc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jsc OCA], [https://pdbe.org/6jsc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jsc RCSB], [https://www.ebi.ac.uk/pdbsum/6jsc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jsc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8NTB9_CORGL Q8NTB9_CORGL] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The crystal structures of the conserved region domains of HtaA and HtaB, which act as heme binding/transport proteins in the heme uptake machinery in Corynebacterium glutamicum, are determined for the first time. The molecular mechanism of heme transfer among these proteins is proposed based on the spectroscopic and structural analyses.

Structural basis for the heme transfer reaction in heme uptake machinery from Corynebacteria.,Muraki N, Kitatsuji C, Okamoto Y, Uchida T, Ishimori K, Aono S Chem Commun (Camb). 2019 Nov 14;55(92):13864-13867. doi: 10.1039/c9cc07369h. PMID:31670736<ref>PMID:31670736</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6jsc" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: Corynebacterium glutamicum ATCC 13032]]
[[Category: Large Structures]]
[[Category: Aono S]]
[[Category: Muraki N]]