View source for 6jzd


==Crystal structure of peptide-bound VASH2-SVBP complex==
<StructureSection load='6jzd' size='340' side='right'caption='[[6jzd]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jzd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JZD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.479&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jzd OCA], [https://pdbe.org/6jzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jzd RCSB], [https://www.ebi.ac.uk/pdbsum/6jzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jzd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VASH2_MOUSE VASH2_MOUSE] Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:29146868). Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis (PubMed:19204325).<ref>PMID:19204325</ref> <ref>PMID:29146868</ref> 

==See Also==
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Chen Z]]
[[Category: Ling Y]]
[[Category: Zeyuan G]]
[[Category: Zhu L]]