View source for 6jzt


==Structure of the bacterial flagellar hook from Salmonella typhimurium==
<SX load='6jzt' size='340' side='right' viewer='molstar' caption='[[6jzt]], [[Resolution|resolution]] 7.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jzt]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JZT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jzt OCA], [https://pdbe.org/6jzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jzt RCSB], [https://www.ebi.ac.uk/pdbsum/6jzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jzt ProSAT]</span></td></tr>
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== Function ==
[https://www.uniprot.org/uniprot/FLGE_SALTY FLGE_SALTY] 
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== Publication Abstract from PubMed ==
The bacterial flagellum is a large molecular complex composed of thousands of protein subunits for motility. The filamentous part of the flagellum, which is called the axial structure, consists of the filament, the hook, and the rods, with other minor components-the cap protein and the hook associated proteins. They share a common basic architecture of subunit arrangement, but each part shows quite distinct mechanical properties to achieve its specific function. The distal rod and the hook are helical assemblies of a single protein, FlgG and FlgE, respectively. They show a significant sequence similarity but have distinct mechanical characteristics. The rod is a rigid, straight cylinder, whereas the hook is a curved tube with high bending flexibility. Here, we report a structural model of the rod constructed by using the crystal structure of a core fragment of FlgG with a density map obtained previously by electron cryomicroscopy. Our structural model suggests that a segment called L-stretch plays a key role in achieving the distinct mechanical properties of the rod using a structurally similar component protein to that of the hook.

Architecture of the Bacterial Flagellar Distal Rod and Hook of Salmonella.,Saijo-Hamano Y, Matsunami H, Namba K, Imada K Biomolecules. 2019 Jul 7;9(7). pii: biom9070260. doi: 10.3390/biom9070260. PMID:31284631<ref>PMID:31284631</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 6jzt" style="background-color:#fffaf0;"></div>

==See Also==
*[[Flagellar protein 3D structures|Flagellar protein 3D structures]]
== References ==
<references/>
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[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Imada K]]
[[Category: Matsunami H]]
[[Category: Namba K]]
[[Category: Saijo-Hamano Y]]