View source for 6kjc


==lovastatin esterase PcEST, wild type==
<StructureSection load='6kjc' size='340' side='right'caption='[[6kjc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6kjc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_rubens_Wisconsin_54-1255 Penicillium rubens Wisconsin 54-1255]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KJC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.297&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kjc OCA], [https://pdbe.org/6kjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kjc RCSB], [https://www.ebi.ac.uk/pdbsum/6kjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kjc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PCEST_PENRW PCEST_PENRW] Esterase that can hydrolyze the side chain of lovastatin to produce monacolin J (PubMed:28619444, PubMed:31839596). Is also able to hydrolyze the side chains of mevastatin and pravastatin, but not simvastatin (PubMed:28619444).<ref>PMID:28619444</ref> <ref>PMID:31839596</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Penicillium rubens Wisconsin 54-1255]]
[[Category: Liang YJ]]
[[Category: Lu XF]]