View source for 6m37


==The crystal structure of B. subtilis RsbV/RsbW complex in the hexagonal crystal form==
<StructureSection load='6m37' size='340' side='right'caption='[[6m37]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6m37]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M37 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m37 OCA], [https://pdbe.org/6m37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m37 RCSB], [https://www.ebi.ac.uk/pdbsum/6m37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m37 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RSBW_BACSU RSBW_BACSU] Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).<ref>PMID:1592822</ref> <ref>PMID:8144446</ref> <ref>PMID:8468294</ref> 

==See Also==
*[[Anti-sigma factor antagonist 3D structures|Anti-sigma factor antagonist 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Kim DY]]
[[Category: Kwon E]]
[[Category: Pathak D]]