View source for 6m67


==The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation==
<StructureSection load='6m67' size='340' side='right'caption='[[6m67]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6m67]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M67 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M67 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANX1, MRS1, UNQ2529/PRO6028 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m67 OCA], [http://pdbe.org/6m67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m67 RCSB], [http://www.ebi.ac.uk/pdbsum/6m67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m67 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN]] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Bo, Z]]
[[Category: Jin, Q]]
[[Category: Xiang, Z]]
[[Category: Xiaokang, Z]]
[[Category: Ye, S]]
[[Category: Atp release]]
[[Category: Heptameric channel]]
[[Category: Pannexin 1]]
[[Category: Transport protein]]