View source for 6m6i


==Structure of HSV2 B-capsid portal vertex==
<StructureSection load='6m6i' size='340' side='right'caption='[[6m6i]], [[Resolution|resolution]] 4.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6m6i]] is a 17 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_2 Human alphaherpesvirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M6I FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m6i OCA], [https://pdbe.org/6m6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m6i RCSB], [https://www.ebi.ac.uk/pdbsum/6m6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m6i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MCP_HHV2H MCP_HHV2H] Self-assembles to form an icosahedral capsid with a T=16 symmetry, about 200 nm in diameter, and consisting of 150 hexons and 12 pentons (total of 162 capsomers). Hexons form the edges and faces of the capsid and are each composed of six MCP molecules. In contrast, one penton is found at each of the 12 vertices. Eleven of the pentons are MCP pentamers, while the last vertex is occupied by the portal complex. The capsid is surrounded by a layer of proteinaceous material designated the tegument which, in turn, is enclosed in an envelope of host cell-derived lipids containing virus-encoded glycoproteins.
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</StructureSection>
[[Category: Human alphaherpesvirus 2]]
[[Category: Large Structures]]
[[Category: Wang N]]
[[Category: Wang XX]]