View source for 6ov1


==Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity==
<StructureSection load='6ov1' size='340' side='right'caption='[[6ov1]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ov1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OV1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ov1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ov1 OCA], [https://pdbe.org/6ov1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ov1 RCSB], [https://www.ebi.ac.uk/pdbsum/6ov1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ov1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNPA_STAAU RNPA_STAAU] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Colquhoun J]]
[[Category: Das C]]
[[Category: Dunman P]]
[[Category: Flaherty DP]]
[[Category: Ha L]]
[[Category: Noinaj N]]