View source for 6p06


==Ternary structure of the E52D mutant of ANT-4 with Neomycin and AMPCPP==
<StructureSection load='6p06' size='340' side='right'caption='[[6p06]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6p06]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._(in:_Bacteria) Bacillus sp. (in: Bacteria)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P06 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NMY:NEOMYCIN'>NMY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p06 OCA], [https://pdbe.org/6p06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p06 RCSB], [https://www.ebi.ac.uk/pdbsum/6p06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p06 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KANU_BACSP KANU_BACSP] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Cuneo MJ]]
[[Category: Selvaraj B]]