View source for 6qgp


==Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-0769==
<StructureSection load='6qgp' size='340' side='right'caption='[[6qgp]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6qgp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QGP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.942&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=J2E:1-cycloheptyl-3-[3-(cyclopentyloxy)-4-methoxyphenyl]-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one'>J2E</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgp OCA], [https://pdbe.org/6qgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qgp RCSB], [https://www.ebi.ac.uk/pdbsum/6qgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8WQX9_9TRYP Q8WQX9_9TRYP] 

==See Also==
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Blaazer AR]]
[[Category: Brown DG]]
[[Category: Leurs R]]
[[Category: Singh AK]]
[[Category: Zara L]]
[[Category: De Esch IJP]]