View source for 6qsh


==Crystal structure of the hybrid bioinorganic complex of Pizza6S linked by the 1:2 Ce-substituted Keggin==
<StructureSection load='6qsh' size='340' side='right'caption='[[6qsh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6qsh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QSH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JGH:1 2+Ce-substituted+Keggin'>JGH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsh OCA], [https://pdbe.org/6qsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qsh RCSB], [https://www.ebi.ac.uk/pdbsum/6qsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsh ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Novel bioinorganic hybrid materials based on proteins and inorganic clusters have enormous potential for the development of hybrid catalysts that synergistically combine properties of both materials. Here we report the creation of hybrid assemblies between a computationally designed symmetrical protein Pizza6-S and different polyoxometalates with matching symmetry: the tellurotungstic Anderson-Evans (Na6[TeW6O24].22H2O) (TEW); Keggin (H4[SiW12O40].6H2O) (STA); and 1 : 2 CeIII-substituted Keggin (K11[CeIII[PW11O39]2].20H2O) (Ce-K). This results in the formation of complexes with clearly defined stoichiometries in solution. Crystal structures validate the complexes as building blocks for the formation of larger assemblies.

Hybrid assemblies of a symmetric designer protein and polyoxometalates with matching symmetry.,Vandebroek L, Noguchi H, Kamata K, Tame JRH, Van Meervelt L, Parac-Vogt TN, Voet ARD Chem Commun (Camb). 2020 Oct 1;56(78):11601-11604. doi: 10.1039/d0cc05071g. PMID:32869783<ref>PMID:32869783</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6qsh" style="background-color:#fffaf0;"></div>

==See Also==
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Kamata K]]
[[Category: Noguchi H]]
[[Category: Parac-Vogt TN]]
[[Category: Tame JRH]]
[[Category: Van Meervelt L]]
[[Category: Vandebroek L]]
[[Category: Voet ARD]]