View source for 6r30


==Aspergillus niger ferulic acid decarboxylase (Fdc) L439G variant in complex with the covalent adduct formed between prFMN cofactor and phenylpropiolic acid (Int1')==
<StructureSection load='6r30' size='340' side='right'caption='[[6r30]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6r30]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R30 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R30 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JQ8:phenylpropiolic+acid'>JQ8</scene>, <scene name='pdbligand=JQZ:prFMN+cofactor+and+phenylpropiolic+acid'>JQZ</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r30 OCA], [https://pdbe.org/6r30 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r30 RCSB], [https://www.ebi.ac.uk/pdbsum/6r30 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r30 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FDC1_ASPNC FDC1_ASPNC] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]<ref>PMID:26083754</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Aspergillus niger]]
[[Category: Large Structures]]
[[Category: Bailey SS]]
[[Category: Leys D]]