View source for 6rng


==Dipeptide Gly-Pro binds to a glycolytic enzyme fructose bisphosphate aldolase==
<StructureSection load='6rng' size='340' side='right'caption='[[6rng]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6rng]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RNG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rng OCA], [https://pdbe.org/6rng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rng RCSB], [https://www.ebi.ac.uk/pdbsum/6rng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rng ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALFC6_ARATH ALFC6_ARATH] Fructose-bisphosphate aldolase that plays a key role in glycolysis and gluconeogenesis (PubMed:21782461). Associates with GAPC1 to the outer mitochondrial membrane, in a redox-dependent manner, leading to binding and bundling of actin. Actin binding and bundling occurs under oxidizing conditions and is reversible under reducing conditions. May be part of a redox-dependent retrograde signal transduction network for adaptation upon oxidative stress (PubMed:23316205).<ref>PMID:21782461</ref> <ref>PMID:23316205</ref> 

==See Also==
*[[Aldolase 3D structures|Aldolase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Shahar A]]
[[Category: Skirycz A]]
[[Category: Wojciechowska I]]
[[Category: Zarivach R]]