View source for 6su0


==Crystal structure of dimethylated RSLex in complex with cucurbit[7]uril==
<StructureSection load='6su0' size='340' side='right'caption='[[6su0]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6su0]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Ralstonia_solanacearum Ralstonia solanacearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SU0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MFU:ALPHA-L-METHYL-FUCOSE'>MFU</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=QQ7:CUCURBIT[7]URIL'>QQ7</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6su0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6su0 OCA], [https://pdbe.org/6su0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6su0 RCSB], [https://www.ebi.ac.uk/pdbsum/6su0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6su0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8XXK6_RALSO Q8XXK6_RALSO] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
A crystalline biohybrid with a 4 : 1 protein : cucurbituril mass ratio is presented. This result was achieved by engineering additional cucurbit[7]uril (Q7) binding sites into a beta-propeller protein. In contrast to the parent protein, Q7-controlled assembly of the engineered variant occurred in solution, as evidenced by NMR and SAXS measurements.

Engineered assembly of a protein-cucurbituril biohybrid.,Guagnini F, Engilberge S, Ramberg KO, Perez J, Crowley PB Chem Commun (Camb). 2020 Jan 2;56(3):360-363. doi: 10.1039/c9cc07198a. PMID:31825399<ref>PMID:31825399</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6su0" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Ralstonia solanacearum]]
[[Category: Crowley PB]]
[[Category: Engilberge S]]
[[Category: Guagnini F]]