View source for 6ucz


==Crystal structure of dihydropteroate synthase from Anaplasma phagocytophilum with bound 6-hydroxymethylpterin-monophosphate==
<StructureSection load='6ucz' size='340' side='right'caption='[[6ucz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ucz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum Anaplasma phagocytophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UCZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PMM:PTERIN-6-YL-METHYL-MONOPHOSPHATE'>PMM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ucz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ucz OCA], [https://pdbe.org/6ucz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ucz RCSB], [https://www.ebi.ac.uk/pdbsum/6ucz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ucz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/S5PWL8_ANAPH S5PWL8_ANAPH] Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.[RuleBase:RU361205]

==See Also==
*[[Dihydropteroate synthase 3D structures|Dihydropteroate synthase 3D structures]]
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</StructureSection>
[[Category: Anaplasma phagocytophilum]]
[[Category: Large Structures]]