View source for 6uf2


==NMR structure of biofilm-related Se0862 from Synechococcus elongatus==
<StructureSection load='6uf2' size='340' side='right'caption='[[6uf2]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6uf2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_7942_=_FACHB-805 Synechococcus elongatus PCC 7942 = FACHB-805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UF2 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uf2 OCA], [https://pdbe.org/6uf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uf2 RCSB], [https://www.ebi.ac.uk/pdbsum/6uf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uf2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q31PX7_SYNE7 Q31PX7_SYNE7] 
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== Publication Abstract from PubMed ==
Biofilms are accumulations of microorganisms embedded in extracellular matrices that protect against external factors and stressful environments. Cyanobacterial biofilms are ubiquitous and have potential for treatment of wastewater and sustainable production of biofuels. But the underlying mechanisms regulating cyanobacterial biofilm formation are unclear. Here, we report the solution NMR structure of a protein, Se0862, conserved across diverse cyanobacterial species and involved in regulation of biofilm formation in the cyanobacterium Synechococcus elongatus PCC 7942. Se0862 is a class alpha+beta protein with alphaalphabetabetabetabetaalphaalpha topology and roll architecture, consisting of a four-stranded beta-sheet that is flanked by four alpha-helices on one side. Conserved surface residues constitute a hydrophobic pocket and charged regions that are likely also present in Se0862 orthologs.

Solution NMR structure of Se0862, a highly conserved cyanobacterial protein involved in biofilm formation.,Zhang N, Chang YG, Tseng R, Ovchinnikov S, Schwarz R, LiWang A Protein Sci. 2020 Nov;29(11):2274-2280. doi: 10.1002/pro.3952. Epub 2020 Oct 24. PMID:32949024<ref>PMID:32949024</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6uf2" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Synechococcus elongatus PCC 7942 = FACHB-805]]
[[Category: LiWang AL]]
[[Category: Zhang N]]