View source for 6vef


==Cryo-EM Structure of Escherichia coli 2-oxoglutarate dehydrogenase E1 component sucA==
<StructureSection load='6vef' size='340' side='right'caption='[[6vef]], [[Resolution|resolution]] 4.08&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6vef]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VEF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.08&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vef OCA], [https://pdbe.org/6vef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vef RCSB], [https://www.ebi.ac.uk/pdbsum/6vef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vef ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ODO1_ECOLI ODO1_ECOLI] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
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</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Gao H]]