View source for 6wgc


==Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)==
<StructureSection load='6wgc' size='340' side='right'caption='[[6wgc]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6wgc]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WGC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WGC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wgc OCA], [https://pdbe.org/6wgc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wgc RCSB], [https://www.ebi.ac.uk/pdbsum/6wgc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wgc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ORC6_YEAST ORC6_YEAST] Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication.<ref>PMID:17825064</ref> <ref>PMID:18006685</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Bai L]]
[[Category: Dodd T]]
[[Category: Ivanov I]]
[[Category: Li H]]
[[Category: Magdalou I]]
[[Category: Riera A]]
[[Category: Schneider S]]
[[Category: Speck C]]
[[Category: Stillman B]]
[[Category: Yan C]]
[[Category: Yuan Z]]