View source for 6wqk


==hnRNPA2 Low complexity domain (LCD) determined by cryoEM==
<StructureSection load='6wqk' size='340' side='right'caption='[[6wqk]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6wqk]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_marginale Anaplasma marginale] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WQK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wqk OCA], [https://pdbe.org/6wqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wqk RCSB], [https://www.ebi.ac.uk/pdbsum/6wqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wqk ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> 
== Function ==
[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.[https://www.uniprot.org/uniprot/X5DSL3_ANAMA X5DSL3_ANAMA] 

==See Also==
*[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Anaplasma marginale]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Boyer DR]]
[[Category: Cao Q]]
[[Category: Cascio D]]
[[Category: Eisenberg DS]]
[[Category: Hughes MP]]
[[Category: Lu J]]
[[Category: Sawaya MR]]