View source for 6xqt


==Extreme malleability of the SARS-CoV-2 3CL Mpro active site cavity facilitates binding of clinical antivirals: Prospects for repurposing existing drugs and ramifications for inhibitor design==
<StructureSection load='6xqt' size='340' side='right'caption='[[6xqt]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XQT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NNA:(1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropyla+mino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide'>NNA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xqt OCA], [https://pdbe.org/6xqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xqt RCSB], [https://www.ebi.ac.uk/pdbsum/6xqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xqt ProSAT]</span></td></tr>
</table>

==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Coates L]]
[[Category: Kneller DW]]
[[Category: Kovalevsky A]]