View source for 6ylp


==EGFP_in_Acidic_env Directionality of Optical Properties of Fluorescent Proteins==
<StructureSection load='6ylp' size='340' side='right'caption='[[6ylp]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YLP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GYS:[(4Z)-2-(1-AMINO-2-HYDROXYETHYL)-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>GYS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ylp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ylp OCA], [https://pdbe.org/6ylp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ylp RCSB], [https://www.ebi.ac.uk/pdbsum/6ylp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ylp ProSAT]</span></td></tr>
</table>
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== Publication Abstract from PubMed ==
Fluorescent molecules are like antennas: The rate at which they absorb light depends on their orientation with respect to the incoming light wave, and the apparent intensity of their emission depends on their orientation with respect to the observer. However, the directions along which the most important fluorescent molecules in biology, fluorescent proteins (FPs), absorb and emit light are generally not known. Our optical and X-ray investigations of FP crystals have now allowed us to determine the molecular orientations of the excitation and emission transition dipole moments in the FPs mTurquoise2, eGFP, and mCherry, and the photoconvertible FP mEos4b. Our results will allow using FP directionality in studies of molecular and biological processes, but also in development of novel bioengineering and bioelectronics applications.

Directionality of light absorption and emission in representative fluorescent proteins.,Myskova J, Rybakova O, Brynda J, Khoroshyy P, Bondar A, Lazar J Proc Natl Acad Sci U S A. 2020 Dec 3. pii: 2017379117. doi:, 10.1073/pnas.2017379117. PMID:33273123<ref>PMID:33273123</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6ylp" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Brynda J]]
[[Category: Lazar J]]
[[Category: Myskova J]]
[[Category: Rybakova O]]