View source for 6ysw


==E. coli anaerobic trifunctional enzyme subunit-alpha in complex with coenzyme A==
<StructureSection load='6ysw' size='340' side='right'caption='[[6ysw]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ysw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YSW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ysw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ysw OCA], [https://pdbe.org/6ysw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ysw RCSB], [https://www.ebi.ac.uk/pdbsum/6ysw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ysw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FADJ_ECOLI FADJ_ECOLI] Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids.<ref>PMID:12270828</ref> <ref>PMID:12535077</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Hynonen MJ]]
[[Category: Sah-Teli SK]]
[[Category: Venkatesan R]]
[[Category: Wierenga RK]]