View source for 6z82


==Thalictrum flavumn Norcoclaurine synthase point mutant in complex with a transition state analoge==
<StructureSection load='6z82' size='340' side='right'caption='[[6z82]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6z82]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thalictrum_flavum_subsp._glaucum Thalictrum flavum subsp. glaucum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z82 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QBW:4-[2-[(phenylmethyl)amino]ethyl]benzene-1,2-diol'>QBW</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z82 OCA], [https://pdbe.org/6z82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z82 RCSB], [https://www.ebi.ac.uk/pdbsum/6z82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z82 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NCS_THLFG NCS_THLFG] Involved in the biosynthesis of the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or berberine. Condenses dopamine and 4-hydroxyphenylacetaldehyde.<ref>PMID:17696451</ref> <ref>PMID:17900926</ref> <ref>PMID:18384289</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thalictrum flavum subsp. glaucum]]
[[Category: Keep NH]]
[[Category: Roddan R]]
[[Category: Sula A]]