View source for 6zig


==Topological model of the p2 virion baseplate in activated conformation (closed Tal trimer)==
<StructureSection load='6zig' size='340' side='right'caption='[[6zig]], [[Resolution|resolution]] 42.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6zig]] is a 33 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_virus_P2 Lactococcus virus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZIG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 42.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zig OCA], [https://pdbe.org/6zig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zig RCSB], [https://www.ebi.ac.uk/pdbsum/6zig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zig ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RBP_BPLP2 RBP_BPLP2] Binds to the host phosphopolysaccharides at the onset of infection. Upon activation by calcium, the receptor binding proteins change their conformation, presenting their binding sites to the host, and a channel opens at the bottom of the baseplate for DNA ejection.<ref>PMID:20351260</ref> <ref>PMID:24027307</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Lactococcus virus P2]]
[[Category: Large Structures]]
[[Category: Cambillau C]]
[[Category: Goulet A]]
[[Category: Spinelli S]]