View source for 7anc


==MlghC, GDP-mannoheptose C4 reductase from Campylobacter jejuni with NADP bound==
<StructureSection load='7anc' size='340' side='right'caption='[[7anc]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7anc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ANC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ANC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7anc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7anc OCA], [https://pdbe.org/7anc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7anc RCSB], [https://www.ebi.ac.uk/pdbsum/7anc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7anc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q0P8I6_CAMJE Q0P8I6_CAMJE] Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.[HAMAP-Rule:MF_00956]
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</StructureSection>
[[Category: Campylobacter jejuni]]
[[Category: Large Structures]]
[[Category: Naismith JH]]
[[Category: Woodward L]]