View source for 7azp


==Structure of the human mitochondrial HSPD1 single ring==
<StructureSection load='7azp' size='340' side='right'caption='[[7azp]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7azp]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AZP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7azp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7azp OCA], [https://pdbe.org/7azp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7azp RCSB], [https://www.ebi.ac.uk/pdbsum/7azp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7azp ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Autosomal dominant spastic paraplegia type 13;Pelizaeus-Merzbacher-like disease due to HSPD1 mutation. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

==See Also==
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Feasey MC]]
[[Category: Klebl DP]]
[[Category: Muench SP]]