View source for 7bcv


==Brevibacterium linens encapsulin structure==
<StructureSection load='7bcv' size='340' side='right'caption='[[7bcv]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7bcv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacterium_linens Brevibacterium linens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BCV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bcv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bcv OCA], [https://pdbe.org/7bcv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bcv RCSB], [https://www.ebi.ac.uk/pdbsum/7bcv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bcv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENCAP_BRELN ENCAP_BRELN] Shell component of a type 1 encapsulin nanocompartment. Assembles into proteinaceous shells 23-24 nm in diameter with 2-2.5 nm thick walls. Endogenous cargo protein DyP (dye-decolorizing peroxidase) is targeted to the interior via its C-terminal extension; only 1 DyP hexamer is incorporated into each shell. Empty shells can be isolated in the absence of cargo (PubMed:19172747, PubMed:27355101, PubMed:29166561). Cargo encapsulation probably precedes assembly of the nanocompartment; may assemble or disassemble via dimers, subcomplexes with a distinct preference for even numbers of subunits are detected (Probable) (PubMed:27355101). Nanocompartments are stable against mechanical forces; loaded nanocompartments are less stable than empty ones (PubMed:27355101). Nanocompartments are stable between pH 5-10; they aggregate at pH 9-10 and start to disassemble at pH 11. They are stable in 1M NaCl, 1 M MgCl(2) and 1M CaCl(2), unstable in 20% DMSO (dimethylsulfoxide) and are stable in 20% but not 40% ethanol (PubMed:29166561).<ref>PMID:19172747</ref> <ref>PMID:27355101</ref> <ref>PMID:29166561</ref> <ref>PMID:27355101</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Brevibacterium linens]]
[[Category: Large Structures]]
[[Category: Allende-Ballestero C]]
[[Category: Caston JR]]
[[Category: Cornelissen JJLM]]
[[Category: Klem R]]
[[Category: Luque D]]