View source for 7bp3


==Cryo-EM structure of the human MCT2==
<StructureSection load='7bp3' size='340' side='right'caption='[[7bp3]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7bp3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BP3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bp3 OCA], [https://pdbe.org/7bp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bp3 RCSB], [https://www.ebi.ac.uk/pdbsum/7bp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bp3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MOT2_HUMAN MOT2_HUMAN] Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate (PubMed:9786900, PubMed:32415067). Dimerization is functionally required and both subunits work cooperatively in transporting substrate (PubMed:32415067).<ref>PMID:32415067</ref> <ref>PMID:9786900</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Guo J]]
[[Category: Jin Q]]
[[Category: Ye S]]
[[Category: Zhang B]]
[[Category: Zhang X]]