View source for 7cge


==The overall structure of nucleotide free MlaFEDB complex==
<StructureSection load='7cge' size='340' side='right'caption='[[7cge]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7cge]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CGE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CGE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cge OCA], [https://pdbe.org/7cge PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cge RCSB], [https://www.ebi.ac.uk/pdbsum/7cge PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cge ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MLAB_ECOLI MLAB_ECOLI] Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane (PubMed:19383799, PubMed:27529189). MlaB plays critical roles in both the assembly and activity of the complex. May act by modulating MlaF structure and stability (PubMed:27529189).<ref>PMID:19383799</ref> <ref>PMID:27529189</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Chi XM]]
[[Category: Fan QX]]
[[Category: Li YY]]
[[Category: Liang K]]
[[Category: Zhang YY]]
[[Category: Zhou Q]]