View source for 7cqz


==crystal structure of mouse FAM46C (TENT5C)==
<StructureSection load='7cqz' size='340' side='right'caption='[[7cqz]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7cqz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CQZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3496976&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cqz OCA], [https://pdbe.org/7cqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cqz RCSB], [https://www.ebi.ac.uk/pdbsum/7cqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cqz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TET5C_MOUSE TET5C_MOUSE] Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein and may be involved in induction of cell death.<ref>PMID:28931820</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Gao S]]
[[Category: Hu JL]]
[[Category: Zhang H]]