View source for 7ctv


==Crystal structure of Arabidopsis thaliana SOBIR1 kinase domain D489A mutant in complex with AMP-PNP and magnesium==
<StructureSection load='7ctv' size='340' side='right'caption='[[7ctv]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ctv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CTV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8856113&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ctv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ctv OCA], [https://pdbe.org/7ctv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ctv RCSB], [https://www.ebi.ac.uk/pdbsum/7ctv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ctv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SBIR1_ARATH SBIR1_ARATH] Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death (PubMed:19616764). Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity (PubMed:27251392). Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission (PubMed:20081191).<ref>PMID:19616764</ref> <ref>PMID:20081191</ref> <ref>PMID:27251392</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Gu TY]]
[[Category: Wang YL]]
[[Category: Wei X]]
[[Category: Xin FJ]]