View source for 7dl9


==Crystal structure of nucleoside transporter NupG==
<StructureSection load='7dl9' size='340' side='right'caption='[[7dl9]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7dl9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DL9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dl9 OCA], [https://pdbe.org/7dl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dl9 RCSB], [https://www.ebi.ac.uk/pdbsum/7dl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dl9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUPG_ECOLI NUPG_ECOLI] Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force. Can transport uridine, adenosine, inosine, guanosine, thymidine and cytidine. Can also transport xanthosine, but with a very low affinity.<ref>PMID:11466294</ref> <ref>PMID:15513740</ref> <ref>PMID:15678184</ref> <ref>PMID:3311747</ref> <ref>PMID:374403</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Deng D]]
[[Category: Wang C]]
[[Category: Xiao QJ]]