View source for 7eji


==Crystal structure of KRED F147L/L153Q/Y190P/L199A/M205F/M206F variant and methyl methacrylate complex==
<StructureSection load='7eji' size='340' side='right'caption='[[7eji]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7eji]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lentilactobacillus_kefiri Lentilactobacillus kefiri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EJI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.560016&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=J66:2-oxidanylisoindole-1,3-dione'>J66</scene>, <scene name='pdbligand=J69:methyl+2-methylprop-2-enoate'>J69</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7eji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7eji OCA], [https://pdbe.org/7eji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7eji RCSB], [https://www.ebi.ac.uk/pdbsum/7eji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7eji ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RADH_LENKE RADH_LENKE] NADP-dependent (R)-specific alcohol dehydrogenase (ADH) with a broad substrate specificity, able to catalyze in vitro the stereoselective reduction of several aliphatic and aromatic ketones as well as beta-keto esters to the corresponding enantiomerically pure alcohols.<ref>PMID:26644568</ref> 

==See Also==
*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Lentilactobacillus kefiri]]
[[Category: Cui J]]
[[Category: Huang X]]
[[Category: Wang B]]
[[Category: Zhao H]]
[[Category: Zhou J]]