View source for 7ene


==Crystal structure of MERS-CoV 3CLpro in complex with the non-covalent inhibitor WU-04==
<StructureSection load='7ene' size='340' side='right'caption='[[7ene]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ene]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ENE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ENE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.98&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J7R:~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide'>J7R</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ene FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ene OCA], [https://pdbe.org/7ene PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ene RCSB], [https://www.ebi.ac.uk/pdbsum/7ene PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ene ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0A7E693_MERS A0A0A7E693_MERS] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Middle East respiratory syndrome-related coronavirus]]
[[Category: Hou N]]
[[Category: Hu Q]]
[[Category: Peng C]]