View source for 7faw


==Structure of LW domain from Yeast==
<StructureSection load='7faw' size='340' side='right'caption='[[7faw]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7faw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FAW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FAW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.438&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7faw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7faw OCA], [https://pdbe.org/7faw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7faw RCSB], [https://www.ebi.ac.uk/pdbsum/7faw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7faw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TFS2_YEAST TFS2_YEAST] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.  Can promote the transfer of one strand of a double-stranded DNA molecule to a homologous single strand and thus may be involved in recombination.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Gao J]]
[[Category: Liao S]]
[[Category: Tu X]]