View source for 7fdn


==Crystal structure of transcription factor WER in complex with EGL3==
<StructureSection load='7fdn' size='340' side='right'caption='[[7fdn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7fdn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FDN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fdn OCA], [https://pdbe.org/7fdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fdn RCSB], [https://www.ebi.ac.uk/pdbsum/7fdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fdn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EGL1_ARATH EGL1_ARATH] Transcription activator, when associated with MYB75/PAP1, MYB90/PAP2 or TT2. Involved in epidermal cell fate specification. Regulates negatively stomata formation but promotes trichome formation. Together with MYB66/WER, promotes the formation of non-hair cells in root epidermis cells in the N position. Whereas together with CPC, promotes the formation of hair cells in root epidermis cells in the H position by inhibiting non-hair cell formation. Seems also to play a role in the activation of anthocyanin biosynthesis, probably together with MYB75/PAP1. Involved in seed mucilage production. Activates the transcription of GL2.<ref>PMID:12917293</ref> <ref>PMID:12956536</ref> <ref>PMID:14627722</ref> <ref>PMID:15361138</ref> <ref>PMID:15590742</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Luo Q]]
[[Category: Wang B]]