View source for 7fin


==Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GIPR-Gs complex==
<StructureSection load='7fin' size='340' side='right'caption='[[7fin]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7fin]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=GGL:GAMMA-L-GLUTAMIC+ACID'>GGL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fin OCA], [https://pdbe.org/7fin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fin RCSB], [https://www.ebi.ac.uk/pdbsum/7fin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fin ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

==See Also==
*[[Glucose-dependent Insulinotropic Polypeptide Receptor|Glucose-dependent Insulinotropic Polypeptide Receptor]]
*[[Transducin 3D structures|Transducin 3D structures]]
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Synthetic construct]]
[[Category: Chang RL]]
[[Category: Chen LN]]
[[Category: Chen Y]]
[[Category: Cong ZT]]
[[Category: Dai AT]]
[[Category: Feng WB]]
[[Category: Hang KN]]
[[Category: Liang AY]]
[[Category: Ming QQ]]
[[Category: Wang M]]
[[Category: Wang MW]]
[[Category: Wu BL]]
[[Category: Xia T]]
[[Category: Xu HE]]
[[Category: Xu PY]]
[[Category: Yang DH]]
[[Category: Zhang C]]
[[Category: Zhang Y]]
[[Category: Zhao Fh]]
[[Category: Zhao LH]]
[[Category: Zhou QT]]
[[Category: Zou XY]]