View source for 7hsa


==PanDDA analysis group deposition -- Crystal Structure of FatA in complex with Z1267773765==
<StructureSection load='7hsa' size='340' side='right'caption='[[7hsa]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7hsa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7HSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7HSA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.776&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=W0G:(3~{R})-1-(2-fluorophenyl)-3-(methylamino)pyrrolidin-2-one'>W0G</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7hsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7hsa OCA], [https://pdbe.org/7hsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7hsa RCSB], [https://www.ebi.ac.uk/pdbsum/7hsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7hsa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FATA1_ARATH FATA1_ARATH] Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for oleoyl-ACP versus other acyl-ACPs. Substrate preference is 18:1 > 18:0 > 16:1.<ref>PMID:12061798</ref> <ref>PMID:22002626</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Aschenbrenner JC]]
[[Category: Fairhead M]]
[[Category: Fearon D]]
[[Category: Koekemoer L]]
[[Category: Kot E]]
[[Category: Marx ML]]
[[Category: Montgomery MG]]
[[Category: Mulholland NP]]
[[Category: Ni X]]
[[Category: Tomlinson CWE]]
[[Category: Wright ND]]
[[Category: Von Delft F]]