View source for 7jic


==Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment==
<StructureSection load='7jic' size='340' side='right'caption='[[7jic]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7jic]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JIC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jic OCA], [https://pdbe.org/7jic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jic RCSB], [https://www.ebi.ac.uk/pdbsum/7jic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jic ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CD19_HUMAN CD19_HUMAN] Common variable immunodeficiency. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/CD19_HUMAN CD19_HUMAN] Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

==See Also==
*[[CD81|CD81]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Blacklow SC]]
[[Category: Kruse AC]]
[[Category: Rawson S]]
[[Category: Susa KJ]]