View source for 7jvt


==Crystal structure of a lambda-186 hybrid repressor==
<StructureSection load='7jvt' size='340' side='right'caption='[[7jvt]], [[Resolution|resolution]] 3.16&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7jvt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_186 Escherichia virus 186] and [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JVT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.16&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jvt OCA], [https://pdbe.org/7jvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jvt RCSB], [https://www.ebi.ac.uk/pdbsum/7jvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jvt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPC1_BP186 RPC1_BP186] Repressor of lysogeny.[https://www.uniprot.org/uniprot/RPC1_LAMBD RPC1_LAMBD] Repressor protein CI allows phage lambda to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein CI to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
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</StructureSection>
[[Category: Escherichia virus 186]]
[[Category: Escherichia virus Lambda]]
[[Category: Large Structures]]
[[Category: Bruning JB]]
[[Category: Shearwin KE]]
[[Category: Truong JQ]]