View source for 7kae


==Rop protein variant with a buried tryptophan==
<StructureSection load='7kae' size='340' side='right'caption='[[7kae]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7kae]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KAE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kae OCA], [https://pdbe.org/7kae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kae RCSB], [https://www.ebi.ac.uk/pdbsum/7kae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kae ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.

==See Also==
*[[Rop protein|Rop protein]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Gallagher DT]]
[[Category: Hoopes JT]]
[[Category: Karageorgos I]]