View source for 7khs


==OgOGA IN COMPLEX WITH LIGAND 55==
<StructureSection load='7khs' size='340' side='right'caption='[[7khs]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7khs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oceanicola_granulosus_HTCC2516 Oceanicola granulosus HTCC2516]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KHS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=WG4:N-(5-{[(5S)-7-(5-methylimidazo[1,2-a]pyrimidin-7-yl)-2,7-diazaspiro[4.4]nonan-2-yl]methyl}-1,3-thiazol-2-yl)acetamide'>WG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7khs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7khs OCA], [https://pdbe.org/7khs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7khs RCSB], [https://www.ebi.ac.uk/pdbsum/7khs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7khs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OGA_OCEGH OGA_OCEGH] Cleaves GlcNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrate (in vitro).<ref>PMID:20863279</ref> 

==See Also==
*[[O-GlcNAcase|O-GlcNAcase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oceanicola granulosus HTCC2516]]
[[Category: Shaffer PL]]