View source for 7klj


==Crystal structure of the WD-repeat domain of human KIF21A==
<StructureSection load='7klj' size='340' side='right'caption='[[7klj]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7klj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KLJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7klj OCA], [https://pdbe.org/7klj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7klj RCSB], [https://www.ebi.ac.uk/pdbsum/7klj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7klj ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KI21A_HUMAN KI21A_HUMAN] Congenital fibrosis of extraocular muscles. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/KI21A_HUMAN KI21A_HUMAN] Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity (By similarity).

==See Also==
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Dong A]]
[[Category: Edwards AM]]
[[Category: Halabelian L]]
[[Category: Hutchinson A]]
[[Category: Loppnau P]]
[[Category: Seitova A]]
[[Category: Zeng H]]