View source for 7ksa


==Crystal structure of human CYP3A4 with the caged inhibitor==
<StructureSection load='7ksa' size='340' side='right'caption='[[7ksa]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KSA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=X8P:(tert-butyl+{1-[(1-oxo-3-phenyl-1-{[3-(pyridin-3-yl-kappaN)prop-1-en-1-yl]amino}propan-2-yl)sulfanyl]-3-phenylpropan-2-yl}carbamate)(6,6-dimethyl-2,2-bipyridine-kappa~2~N~1~,N~1~)(1~2~,2~2~ 2~6~,3~2~-terpyridine-kappa~3~N~1^{1~},N~2^{1~},N~3^{1~})ruthenium'>X8P</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ksa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ksa OCA], [https://pdbe.org/7ksa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ksa RCSB], [https://www.ebi.ac.uk/pdbsum/7ksa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ksa ProSAT]</span></td></tr>
</table>

==See Also==
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sevrioukova IS]]