View source for 7ljc


==Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein==
<StructureSection load='7ljc' size='340' side='right'caption='[[7ljc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ljc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LJC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=G4C:2-[2,6-bis(chloranyl)phenyl]-1-[(1~{S},3~{R})-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]ethanone'>G4C</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SK0:(1~{R})-6-chloranyl-1-phenyl-2,3,4,5-tetrahydro-1~{H}-3-benzazepine-7,8-diol'>SK0</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ljc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ljc OCA], [https://pdbe.org/7ljc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ljc RCSB], [https://www.ebi.ac.uk/pdbsum/7ljc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ljc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DRD1_HUMAN DRD1_HUMAN] Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

==See Also==
*[[Dopamine receptor 3D structures|Dopamine receptor 3D structures]]
*[[Transducin 3D structures|Transducin 3D structures]]
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Cheng X]]
[[Category: Guo J]]
[[Category: Huang X-P]]
[[Category: Jiang H]]
[[Category: Jiang Y]]
[[Category: Krumm B]]
[[Category: Liu Y]]
[[Category: Melcher K]]
[[Category: Roth BL]]
[[Category: Wang L]]
[[Category: Wang Y]]
[[Category: Xu HE]]
[[Category: Yi W]]
[[Category: Zhang C]]
[[Category: Zhang H]]
[[Category: Zhang Y]]
[[Category: Zhou XE]]
[[Category: Zhuang Y]]