View source for 7n2t


==O-acetylserine sulfhydrylase from Citrullus vulgaris in the internal aldimine state, with citrate bound==
<StructureSection load='7n2t' size='340' side='right'caption='[[7n2t]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7n2t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrullus_lanatus_subsp._vulgaris Citrullus lanatus subsp. vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N2T FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n2t OCA], [https://pdbe.org/7n2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n2t RCSB], [https://www.ebi.ac.uk/pdbsum/7n2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n2t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CYSK_CITLA CYSK_CITLA] Produces L-cysteine from O-acetyl-L-serine and hydrogen sulfide. Can also use pyrazole and 3,4-dihydroxypyridine instead of the hydrogen sulfide to produce two plant specific non-protein amino acids beta-pyrazolylalanine and L-mimosine.<ref>PMID:8280125</ref> <ref>PMID:9013806</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Citrullus lanatus subsp. vulgaris]]
[[Category: Large Structures]]
[[Category: Bingman CA]]
[[Category: Buller AR]]
[[Category: Smith JL]]