View source for 7n2w


==The crystal structure of an FMN-dependent NADH-azoreductase, AzoA in complex with Red 40==
<StructureSection load='7n2w' size='340' side='right'caption='[[7n2w]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7n2w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_MGH_78578 Klebsiella pneumoniae subsp. pneumoniae MGH 78578]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N2W FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=05G:6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]naphthalene-2-sulfonic+acid'>05G</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n2w OCA], [https://pdbe.org/7n2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n2w RCSB], [https://www.ebi.ac.uk/pdbsum/7n2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n2w ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A6TCS9_KLEP7 A6TCS9_KLEP7] Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.[HAMAP-Rule:MF_01216]  Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.[HAMAP-Rule:MF_01216]
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</StructureSection>
[[Category: Klebsiella pneumoniae subsp. pneumoniae MGH 78578]]
[[Category: Large Structures]]
[[Category: Almo SC]]
[[Category: Arcinas AJ]]
[[Category: Fedorov E]]
[[Category: Ghosh A]]
[[Category: Kelly L]]