View source for 7op2


==Chadox1/ Chimpanzee adenovirus Y25 fiber knob protein==
<StructureSection load='7op2' size='340' side='right'caption='[[7op2]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7op2]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Chimpanzee_adenovirus_Y25 Chimpanzee adenovirus Y25]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OP2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7op2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7op2 OCA], [https://pdbe.org/7op2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7op2 RCSB], [https://www.ebi.ac.uk/pdbsum/7op2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7op2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/G9G864_9ADEN G9G864_9ADEN] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
[Figure: see text].

ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.,Baker AT, Boyd RJ, Sarkar D, Teijeira-Crespo A, Chan CK, Bates E, Waraich K, Vant J, Wilson E, Truong CD, Lipka-Lloyd M, Fromme P, Vermaas J, Williams D, Machiesky L, Heurich M, Nagalo BM, Coughlan L, Umlauf S, Chiu PL, Rizkallah PJ, Cohen TS, Parker AL, Singharoy A, Borad MJ Sci Adv. 2021 Dec 3;7(49):eabl8213. doi: 10.1126/sciadv.abl8213. Epub 2021 Dec 1. PMID:34851659<ref>PMID:34851659</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 7op2" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Chimpanzee adenovirus Y25]]
[[Category: Large Structures]]
[[Category: Baker AT]]
[[Category: Lipka-Lloyd M]]
[[Category: Parker AL]]
[[Category: Rizkallah PJ]]
[[Category: Teijeira Crespo A]]