View source for 7p9l


==N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine-6-phosphate==
<StructureSection load='7p9l' size='340' side='right'caption='[[7p9l]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7p9l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plesiomonas_shigelloides_302-73 Plesiomonas shigelloides 302-73] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4QY:BETA-N-ACETYLGLUCOSAMINE-6-PHOSPHATE'>4QY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9l OCA], [https://pdbe.org/7p9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9l RCSB], [https://www.ebi.ac.uk/pdbsum/7p9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/R8APY9_PLESH R8APY9_PLESH] Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.[HAMAP-Rule:MF_01271][https://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST] Not known; suppressor of MIF2 mutations.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Plesiomonas shigelloides 302-73]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Ames JR]]
[[Category: Harmer NJ]]
[[Category: Isupov MN]]
[[Category: Roy S]]